Glossary entry

English term or phrase:

Spending Function

Arabic translation:

دالة بولوك للإنفاق

Added to glossary by Liliane Hatem
Aug 13, 2012 17:19
11 yrs ago
2 viewers *
English term

Spending Function

English to Arabic Medical Medical: Pharmaceuticals Clinical trial
The primary non-inferiority analysis based on a 1.8 margin will be performed using the Pocock α-spending function to control the overall Type I error rate at a two-sided significance level of 0.05.
Change log

Aug 15, 2012 07:35: Liliane Hatem changed "Edited KOG entry" from "<a href="/profile/634318">Fathy Shehatto's</a> old entry - "Spending Function"" to ""دالة بولوك للإنفاق""

Proposed translations

20 mins
Selected

دالة بولوك للإنفاق

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Note added at 20 mins (2012-08-13 17:39:33 GMT)
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دالة بوكوك للإنفاق

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Note added at 29 mins (2012-08-13 17:48:21 GMT)
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skhayat.kau.edu.sa/.../مبادئ%20الاقتصاد%20الكل... - Translate this page
File Format: Microsoft Powerpoint - Quick View
الطلب الكلي هو ”اجمالي الإنفاق المخطط لكافة المشترين في اقتصاد معين ”. ..... على أثر تغير دالة الانفاق الكلي نتيجة لتغير الانفاق الاستثماري على مستوى التوازن

Analysis Of Clinical Trials Using Sas: A Practical Guide - Google Books Result
books.google.com/books?isbn=1590475046...Alex Dmitrienko, Walter Offen - 2005 - Computers - 420 pages
This example was used in Section 4.2.1 to introduce O'Brien-Fleming and Pocock group sequential designs. It is easy to compute error spending functions ...
Note from asker:
Hello Liliane, Any Arabic reference please? Really I translated it the same, but couldn't find any Arabic resource to support my supposition
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4 KudoZ points awarded for this answer.
4 hrs

دالة بوكوك ألفا للإنفاق

Alpha Spending Function:

In the interim monitoring of clinical trials, multiple looks are taken at the accruing results. In such circumstances, akin to multiple testing, the alpha-value at each look must be adjusted in order to preserve the overall Type-1 Error. Alpha spending functions, (the Pocock family is one such set; the Lan-Demets spending function a more specific case) establish these adjusted alpha-values for each interim monitoring point, given the overall alpha. Typically, they establish relatively high alpha-values for early looks, and lower alpha-values for later looks. Thus, they constitute "stopping boundaries," which, when crossed, indicate that statistical significance has been established. When graphed, a typical set of stopping boundaries looks like an inverted V pointing to the right. (horizontal axis represents number of events recorded, vertical axis the standardized value of
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