This site uses cookies.
Some of these cookies are essential to the operation of the site,
while others help to improve your experience by providing insights into how the site is being used.
For more information, please see the ProZ.com privacy policy.
Spanish to English: LOS ENDOCANNABINOIDES COMO UNA FUTURA HERRAMIENTA PARA EL TRATAMIENTO DE CÁNCER General field: Medical Detailed field: Medical (general)
Source text - Spanish RESUMEN
El tratamiento antineoplásico farmacológico se centra en la inhibición de proliferación celular, de células que presentan alto índice mitótico. Estos fármacos no son capaces de diferenciar entre células sanas y enfermas. Esto es responsable de una gran cantidad de efectos adversos: alopecia, alteraciones del sistema gastrointestinal, depresión de médula ósea, alteraciones del comportamiento, potencial carcinogénico, entre otros. Hay muchos grupos de investigación que trabajan en la búsqueda de nuevas moléculas con actividad potencial antineoplásica. Entre los compuestos líderes están el tetrahidrocannabinol y endocannabinoides, como la anandamida. Estudios recientes permiten concluir que esos compuestos ofrecen una alta selectividad sobre células enfermas; esto puede ser considerado como una posibilidad de bajo riesgo de toxicidad. Los tratamientos antineoplásicos, como los de cualquier patología, deberían tener en cuenta los ritmos biológicos con el fin de obtener mejores efectos terapéuticos y un perfil menor de reacciones adversas. El objetivo de este trabajo es dar a conocer los mecanismos de acción de cannabinoides y endocannabinoides en cáncer, los beneficios del futuro tratamiento antineoplásico basado en la acción de estos compuestos sobre el crecimiento de las células cancerosas.
Translation - English SUMMARY
The antineoplastic drug treatment focuses on the inhibition of cell proliferation, those cells which have high mitotic index. However, these drugs are not able to differentiate between healthy cells and the sick. This feature is responsible for a large number of adverse effects, including the alopecia, disorders of the gastrointestinal system, bone marrow depression, changes in behavior and one carcinogenic potential, among others. There are many research groups working in the search for new molecules with potential antineoplastic activity. The composite leaders include tetrahydrocannabinol and endocannabinoids, as anandamide. Recent studies suggest that these compounds offer a high selectivity on diseased cells; this can be considered as a possibility for low risk of toxicity. Finally, all antineoplastic treatments such as of any pathology, should take into account biological rhythms in order to obtain the best therapeutic effects and one less adverse reaction profile. The objective of this work is to understand the mechanisms of action of cannabinoids, the endocannabinoids in cancer and the benefits of future antineoplastic therapy based on the action of these compounds on the growth of cancer cells.
Spanish to English: Un jueves en Medellín General field: Other Detailed field: Journalism
Source text - Spanish Mi esposa y yo vivimos separados. Quiero decir que somos marido y mujer, pero como ella cree que la convivencia mata la pasión, preferimos seguir viviendo cada uno en su propia casa. Yo vivo solo, y ella con sus niños, que son dos, y no hijos míos, sino fruto de su vientre en el primer matrimonio que tuvo, con un arquitecto. Un día, con el pretexto de que estoy medio viejo y una vez me desmayé en un restaurante, ella me pidió las llaves de mi casa. “¿Qué tal que estés solo y te vuelva a dar un patatús y yo no pueda entrar a rescatarte, a llevarte por ejemplo al hospital?”. “O por ejemplo al asilo… tienes razón…”, le dije yo. Y le entregué una copia de las llaves. “Pero debes darme las tuyas tú también, en reciprocidad. ¿Qué tal que un día tus hijos te estén dando una paliza y yo no pueda entrar a rescatarte?”. No sin cierta reticencia, ella accedió.
Ella no ha usado nunca las llaves para entrar en mi casa, que yo sepa, ni yo tampoco he usado las suyas para entrar en su casa cuando ella no está. Solo que el otro día se me metió en la cabeza que algo raro estaba pasando allá. Los hijos se habían ido con el arquitecto toda la semana y la actitud de mi esposa me resultó un poco extraña. En vez de venir a visitarme o de invitarme a comer, sacó unas disculpas absurdas para que no nos viéramos ni el martes ni el miércoles. La idea confusa siguió creciendo en mi cabeza y el jueves por la tarde la llamé por teléfono. Ella me dijo que estaba yendo al cine con Lina, su mejor amiga. El pálpito creció. Corrí a su casa, que está como a 10 manzanas de la mía; el portero me conoce y me dejó pasar aunque, advirtió, “la señora no está”. Subí los ocho pisos en el ascensor. Todo estaba en silencio, en orden. Aunque ella no compra flores, había un ramo de rosas en el florero de la sala. El caos de juguetes de los niños había sido ordenado en la habitación de las dos camas simétricas. Fui al cuarto de mi esposa. La cama tendida; ningún olor extraño. Sin embargo a un lado de la cama había un maletín de viaje. La etiqueta de Avianca, todavía en el asa de la maleta, decía Mr. Ferro
Translation - English My wife and I don’t live together. I mean we are husband and wife, but she believes living together kills passion, so we would prefer to keep living each in our own home. I live alone, and she lives with her two children. Although they aren’t mine, rather the fruit of her womb from her first marriage to an architect. One day, using the excuse that I’m getting on a bit and once fainted in a restaurant, she asked me for the keys to my house.
“What if you are alone and you take a bad turn and I can’t get into your house to save you, and maybe bring you to the hospital?”
“Or perhaps to the nursing home …you’re right,” I told her. And I gave her a spare set of keys. “But in return you have to give me yours. What if one day your children are beating you up and I can’t get in to save you?”
She agreed, reluctantly.
She has never used the keys to get into my house, as far as I’m aware, nor have I used her keys to get into her house when she is not there. It’s just that the other day I got it into my head that something strange was happening there. The kids had left with the architect for the whole week and my wife was acting strange around me. Instead of coming to visit me or inviting me to have dinner, she made up ridiculous excuses not to see me Tuesday or Wednesday. Puzzling thoughts kept growing in my head until she phoned me on Thursday evening. She told me that she was going to the cinema with Lina, her best friend. My hunch grew. I ran to her house, which is about ten blocks away from mine; the doorman knows me and let me in although he informed, “the lady is not in.” I went up the eight floors in the lift. Everything was quiet, in its place. Although she doesn’t buy flowers, there was a bouquet of roses in the vase in the living room. The chaos of the children’s toys had been tidied in the twin bedroom. I went to my wife’s room. The bed was made; not a trace, not a whiff of suspicion. However beside the bed there was a suitcase. The Avianca label, still on the handle, said Mr.Ferro.
French to English: Le sacrifice des platanes du canal du Midi General field: Other Detailed field: Journalism
Source text - French
Ombres tutélaires d'un patrimoine séculaire, les 42.000 platanes qui bordent les quelque 239 km du canal du Midi vont être sacrifiés. Rongée depuis 2006 par un mal incurable répondant au nom de Ceratocystis platani, la voûte arborée fait aujourd'hui l'objet de plans d'abattage et de campagnes de replantation par les pouvoirs publics pour tenter de sauver son classement au patrimoine de l'humanité, décidé par l'Unesco en 1996.
Emblématique de l'ouvrage de Pierre Paul de Riquet, réalisé sous le règne de Louis XIV entre 1666 et 1681, elle encadrait jusqu'alors cette voie navigable appréciée des touristes, qui relie la Garonne à la mer Méditerranée. Construit pour développer le commerce du blé, ce sentier d'eau est l'un des plus anciens canaux d'Europe encore en fonctionnement. D'abord nommé Canal royal en Languedoc, il est rebaptisé par les révolutionnaires canal du Midi en 1789. Ses contemporains le considèrent alors comme le plus grand chantier du XVIIe siècle.
Avec une telle dimension historique et patrimoniale, une majesté qui frappe encore l'#339;il et la mémoire des nouvelles générations, la suppression de cette architecture végétale suscite émoi et inquiétude. Chez les amoureux de la nature mais aussi et surtout chez les élus locaux, qui craignent des conséquences touristiques et un déclassement par l'Unesco, même s'il ne semble «pas à l'ordre du jour» selon le ministère de l'Écologie. Interpellé sur le sujet alors qu'il était mardi à Agde, dans l'Hérault, le président de la République a assuré que le gouvernement s'associerait aux élus locaux pour «sauver» le canal du Midi, un «patrimoine exceptionnel». «C'est un grand malheur et je vais demander à Frédéric Lefebvre et Nathalie Kosciusko-Morizet de vous recevoir», a promis Nicolas Sarkozy à Agnès Jullian, vice-présidente de la région Languedoc-Roussillon.
Translation - English Sacrificing the Plane Trees of the Canal du Midi
Like protective shadows of a century old heritage, the 42,000 plane trees that line the 239 or so kilometres of the Canal du Midi will soon be destroyed. Since 2006, an incurable disease has been threatening their survival. The archway of trees is now being targeted for logging and replantation plans by government bodies in a bid to save their identity and heritage, this decision was made by UNESCO in 1996.
The structure, which is the symbolic work of Pierre Paul de Riquet, was completed during Louis XIV’s rule between 1666 and 1681. Up until now, these trees have framed the navigable waterway which is popular among tourists and connects la Garonne to the Mediterranean Sea. Initially it was built to expand wheat trade and this watercourse is one of the oldest canals in Europe still in use. After it was originally named Canal Royal in Languedoc, it was renamed Canal du Midi by revolutionaries in 1789. People from this period consider it the most remarkable feat of engineering of the 17th Century.
With such historical and ancestral dimension, a majestic edifice which still grabs the attention of new generations, the abolition of this natural architecture provokes feelings of anxiety and concern. This is true for environmentalists and particularly for local representatives, who fear consequences for tourism and a drop in status for UNESCO, even though it may seem to be ‘not on the agenda’ according to the department of Ecology. The president, who was questioned about the subject on Tuesday at Agde, in the department of Herault, assured that the government will join forces with the local electives to save the Canal du Midi, a remarkable heritage. ‘This is a great tragedy and I’m going to ask Frédéric Lefebvre and Nathalie Kosciusko-Morizet to support you’ promised Sarkozy to Jullian, vice president of the region of Langue-doc Rousillan.
More
Less
Translation education
Master's degree - Queen's University Belfast
Experience
Years of experience: 9. Registered at ProZ.com: Oct 2014.
I'm a Professional Freelance Translator from Ireland. I work from Spanish and French into English and, as well as translation I offer other services such as proof-reading, localization, editing and subtitling.
The service I provide is experienced, professional and of a very high standard. In addition, I place a large amount of importance on reliability, communication and building a strong working relationship with my clients. I have experience working on research projects for Newcastle University, the British Council, as well as technical and audiovisual translation projects.
I would be grateful for any opportunities in this field. Thank you!
Expertise